Felix Geisendörfer, one of the node.js contributers released a clean cut, simple guide a while ago to writing node.js applications. He launched a site called nodeguide.com which mostly has a beginner’s guide, a guide for how to convince your boss you should be using node (kind of funny) and a style guide for standardization of indentation, naming, etc.
A short summary of the guides
The beginners guide is pretty short. It teaches you how to install node, run your first hello world, a little about the packaging system and recommends a few web frameworks.
The style guide should be taken with a grain of salt. It’s good to have some standard but style guides have historically never been popular because most people like writing code however they see fit.
The convincing the boss guide is probably the most impressive, in my opinion. It’s very pragmatic and doesn’t try to sell you Node.js as the ultimate solution to every existing problem out there. He quite honestly points out that if you’re just trying to put together a simple web application there really isn’t much that Node can do that other languages/frameworks can’t do just as well. I think he even sells it a bit short, since in my opinion the upsides are more than he mentions.